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Intractable epilepsy and olfactory bulb hamartoma. A case report
Andrew W McEvoy1, Marcello Bartolucci, Thomas Revesz
1Department of Surgical Neurology, The National Hospital for Neurology and Neurosurgery, London, UK. a.mcevoy@ion.ucl.ac.uk
Stereotactic and Functional Neurosurgery
|May 14, 2003
Summary
A rare benign olfactory bulb tumor caused intractable epilepsy in a young man. Surgical removal of this olfactory hamartoma resolved the seizures, highlighting a unique cause of epilepsy.
Area of Science:
- Neurology
- Neurosurgery
- Pathology
Background:
- Intractable epilepsy presents a significant clinical challenge.
- Diagnosing lesions in the olfactory apparatus is often difficult.
- Olfactory tumors are rare but can manifest with neurological symptoms.
Observation:
- A 29-year-old male with intractable epilepsy was evaluated.
- Radiological imaging revealed a calcified lesion in the mesial inferior frontal lobe.
- Electroclinical findings localized the epileptogenic zone to this lesion.
Findings:
- Surgical resection of the lesion was performed.
- Histological examination identified the tumor as a benign hamartoma originating from the olfactory bulb.
- The patient experienced complete seizure resolution post-surgery.
Implications:
- Benign olfactory bulb tumors can serve as a primary epileptic focus.
- This case underscores the diagnostic challenges of olfactory apparatus lesions.
- Surgical intervention for such tumors can lead to epilepsy remission.