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Updated: Sep 26, 2026

Microbial Control and Monitoring Strategies for Cleanroom Environments and Cellular Therapies
Published on: March 17, 2023
Best practice forum: standard high level disinfection protocol development
Cindy J Dawson1, Ruth Nielsen, Douglas E Dawson
1Otolaryngology-Head and Neck Surgery Clinic, Oral Surgery Clinic, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Abstract:
Gluteraldehyde-based high-level disinfection (HLD) poses significant safety risks for staff and patients as well as institutional cost concerns. A value analysis team reviewed HLD practices, available products, and environmental requirements in view of the literature and standards developed by the Occupational Safety and Health Administration (OSHA). Institutional areas were identified and standardized unit-specific educational and competency programs were established. The overall use of gluteraldehyde-based HLD was decreased in this institution based on the findings and policy and procedure modification.
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