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Effective chemical preservation of morphology of urinary erythrocytes

Olga Komarova1, Wim van der Meer, Elena Levtchenko

  • 1Department of Pediatric Nephrology, Institute of Pediatrics, RAMN, Moscow, Russia.

Pediatric Nephrology (Berlin, Germany)
|May 16, 2003
PubMed

Between 2 and 4 h after miction the morphology of urinary erythrocytes has changed, clouding the distinction between glomerular and non-glomerular bleeding in pediatric patients. Glomerular bleeding is characterized by microscopically visible alteration in urinary erythrocytes due to glomerular disease. Fixation by Cellfix, a formaldehyde-based fixative, allows the preservation of the morphology for at least 24 h and can be recommended for clinical practice. In our experience, thiomersal was not effective for preservation of the morphology of erythrocytes.

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