Related Experiment Video
Updated: Sep 26, 2026

DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning
Published on: March 15, 2011
DNA microarrays in clinical practice: past, present, and future
1Plateforme de Génomique, Service de Biochimie et de Biologie Moléculaire, Hôpital Lariboisière (AP-HP), 2, rue Ambroise Paré, F-75010 Paris, France. nicolas.sevenet@lrb.ap-hop-paris.fr
Abstract:
Gene expression is a central concept in molecular biology and forms part of our knowledge of the role of genes in human diseases. Genome-wide monitoring of gene expression using DNA microarrays (allowing the simultaneous assessment of the transcription of tens of thousands of genes, and of their relative expression between normal cells and pathological cells) represents one of the latest breakthroughs in experimental molecular biology and provides unprecedented opportunity to explore the biological processes underlying human diseases by providing a comprehensive survey of a cell's transcriptional landscape. This revolutionary technology ultimately leads to the discovery of new biomarkers for disease diagnosis and prognosis prediction, and of new therapeutic tools. This paper provides an overview of microarray technology and describes some of its recent applications in medicine.
Related Concept Videos
DNA Microarrays
Next-generation Sequencing
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.
Modern Molecular Taxonomy

