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Simple invasive fixation device for fractionated stereotactic LINAC based radiotherapy
O Ganslandt1, R Mueller, W Mueller
1Department of Neurosurgery, University of Erlangen-Nürnberg, Germany.
Acta Neurochirurgica
|May 16, 2003
Summary
A new relocatable fixation device for stereotactic radiotherapy offers excellent reposition accuracy. This innovative system may allow for smaller safety margins, improving treatment precision.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Medical Device Development
Background:
- Fractionated stereotactic radiotherapy requires precise patient fixation.
- Existing fixation methods may have limitations in accuracy or invasiveness.
Purpose of the Study:
- To develop and evaluate a novel, relocatable fixation device for linear accelerator (LINAC)-based stereotactic radiotherapy.
- To assess the accuracy and safety of this new fixation system.
Main Methods:
- A CT- and MRI-compatible stereotactic frame with bone screws and a modified head clamp was designed.
- The device's relocatability and reposition accuracy were prospectively evaluated using phantom studies and patient data.
- Isocenter movements were measured during fractionated radiotherapy in patients with intracranial lesions.
Main Results:
- The fixation device was well-tolerated with no adverse events reported.
- Phantom reposition studies showed mean isocenter shifts of less than 0.4 mm.
- Patient studies demonstrated mean isocenter shifts of approximately 0.6 mm in X, Y, and Z axes.
Conclusions:
- The developed fixation device provides excellent reposition accuracy for stereotactic radiotherapy.
- It demonstrates superiority over non-invasive mask fixation techniques.
- The high accuracy may permit reduced safety margins (1-1.5 mm), enhancing treatment precision.