Related Experiment Video
Updated: Aug 15, 2026

A Mouse Model of Lumbar Spine Instability
Published on: April 23, 2021
Idiopathic symptomatic epidural lipomatosis of the lumbar spine
M Payer1, P Van Schaeybroeck, A Reverdin
1Department of Neurosurgery, University Hospital of Geneva, Switzerland.
Background:
Symptomatic spinal epidural lipomatosis (SEL) of the lumbar spine is a rare disease, often associated with steroid overload. Idiopathic lipomatosis is even much less frequent. Signs and symptoms depend upon the level and degree of nerve root compression. Diagnosis is best based on MRI. Weight reduction can be curative, however after failure of medical treatment or in severe cases surgical decompression should be performed.
Method:
Four patients with severe symptoms of lumbar spinal epidural lipomatosis were treated by surgical decompression. Patient history and neurological examination are described, diagnostic imaging is demonstrated, surgical treatment and outcome are documented. Different surgical techniques including laminectomy, interlaminar fenestration and lateral recess decompression were applied and are discussed.
Findings:
All four patients improved after surgery. No surgical complications were observed. Even though limited to four cases this is the second largest series of operated idiopathic spinal epidural lipomatosis.
Interpretation:
Surgical decompression was effective in improving symptoms in severe lumbar idiopathic spinal epidural lipomatosis.
Related Concept Videos
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Herniated Intervertebral Disc l: Introduction

