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Chiari I malformation and cloacal exstrophy: report of a patient with both defects of blastogenesis
R Shane Tubbs1, Matthew D Smyth, W Jerry Oakes
1Pediatric Neurosurgery, Children's Hospital, Birmingham, Alabama 35233, USA. richard.tubbs@ccc.uab.edu
American Journal of Medical Genetics. Part A
|May 16, 2003
Abstract:
We report on child with Chiari I malformation (CIM) and cloacal exstrophy, a combination of findings that has not been reported previously. CIM and cloacal exstrophy both demonstrate abnormalities that represent maldevelopment of the midline field. This combination of anomalies in this patient suggests an impairment of midline development during blastogenesis.
