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Updated: Sep 26, 2026

A Seminiferous Tubule Squash Technique for the Cytological Analysis of Spermatogenesis Using the Mouse Model
Published on: February 6, 2018
[The involvement of endocrine disrupting chemicals in spermatogenic cell apoptosis]
1Department of Physiology, Medical College of Shantou University, Shantou, Guangdong 515031, China.
Abstract:
Elimination of spermatogenic cells via apoptosis occurs spontaneously under normal physiologic conditions and is often aggravated after chemical-induced testicular impairment. A great amount of pollutants is released into the environment by modern industry, and many of these substances have been confirmed possessing reproductive toxicity, which can affect the reproduction and development of organism. These chemicals have been categorized to endocrine disrupting chemicals(EDCs). Studying spermatogenic cell apoptosis induced by EDCs will enrich and expand the pathway to identify EDCs, and will put forward new expounding of its mechanism. It has important meaning in the field of reproduction toxicology and male fertility.
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