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Related Experiment Videos

Changes in regional left atrial function with aging: evaluation by Doppler tissue imaging.

L Thomas1, K Levett, A Boyd

  • 1Department of Cardiology, Westmead Hospital, Sydney, NSW, Australia. lizat@westgate.wh.usyd.edu.au

European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology
|May 17, 2003
PubMed
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Pulsed and color Doppler tissue imaging reveal that atrial contraction increases with age, compensating for reduced atrial contribution to cardiac filling. These reproducible methods offer unique insights into aging atria.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Gerontology

Background:

  • Aging is associated with changes in cardiac function, including atrial function.
  • Standard echocardiographic methods have limitations in assessing global and regional atrial function.
  • Doppler tissue imaging offers advanced capabilities for evaluating atrial mechanics.

Purpose of the Study:

  • To investigate age-related changes in atrial function using pulsed wave Doppler tissue imaging (PW-DTI) and color Doppler tissue imaging (CD-TI).
  • To assess the reproducibility of PW-DTI and CD-TI in evaluating global and regional atrial function.
  • To test if PW-DTI can detect global atrial function changes similar to standard echocardiography.

Main Methods:

  • Studied 92 healthy subjects divided into younger (<50 years) and older (>=50 years) groups.

Related Experiment Videos

  • Utilized PW-DTI to measure atrial contraction velocity (A' velocity) and CD-TI for segmental atrial wall motion.
  • Compared DTI parameters with conventional measures of atrial function, including atrial emptying fraction and atrial ejection force.

    • Main Results:

    • PW-DTI showed significantly higher A' velocities in older adults compared to younger adults (9.8 vs. 8.5 cm/s).
    • Age correlated significantly with atrial ejection force, atrial fraction, and A' velocity.
    • CD-TI revealed a decremental gradient in longitudinal segmental atrial contraction, with higher velocities in older adults.

    Conclusions:

    • PW-DTI and CD-TI are reproducible techniques for assessing global and segmental atrial contraction.
    • Aging is associated with augmented atrial contractility, which contributes to atrial filling.
    • These Doppler tissue imaging methods provide unique data on atrial function changes with aging.