Atomic force microscopy as a tool for biomedical and biotechnological studies
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Updated: Sep 26, 2026

Bacterial Immobilization for Imaging by Atomic Force Microscopy
Published on: August 10, 2011
Geraldo Antônio Guerrera Cidade1, Lilian Terezinha Costa, Gilberto Weissmüller
1Instituto de Biofísica Carlos Chagas Filho, CCS, Universidade Federal do Rio de Janeiro, UFRJ, Rio de Janeiro, RJ, Brazil. gcidade@biof.ufrj.br
Abstract:
This work presents different applications in progress with the aid of the atomic force microscopy (AFM) technique for biomedical and biotechnological applications, comprising both the acquisition of three-dimensional images and spectroscopic force measurements, in the following systems: first, low-density lipoprotein (LDL)-glycosaminoglycans; second, lectins-polysaccharides; third, mycobacterium leprae cellular wall and Vesicular Stomatites Virus (VSV) with fibronectin laminin, and lipidic membranes; fourth, DNA-complex; and fifth, actin, as well as the development of surface functionalizing protocols and image restoration by means of mathematical techniques.
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