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Mechanical Stimulation-induced Calcium Wave Propagation in Cell Monolayers: The Example of Bovine Corneal Endothelial Cells
Published on: July 16, 2013
Corneal esthesiometry in the healthy horse
Simone Kaps1, Marianne Richter, Bernhard M Spiess
1Department of Small Animals, Ophthalmology Service, University of Zurich, Winterthurerstrasse 260, Switzerland. skaps@vetclinics.unizh.ch
Veterinary Ophthalmology
|May 20, 2003
Summary
This study established reference corneal touch threshold (CTT) values in horses. The dorsal cornea was least sensitive, highlighting regional differences in equine corneal sensitivity.
Area of Science:
- Veterinary Ophthalmology
- Equine Neurology
Background:
- Corneal sensitivity is crucial for ocular health and detecting disease.
- Establishing baseline corneal touch threshold (CTT) values in healthy horses is essential for comparative studies.
Purpose of the Study:
- To determine corneal sensitivity in healthy adult horses.
- To establish reference values for corneal touch threshold (CTT) in equine eyes.
Main Methods:
- Corneal sensitivity was assessed using a Cochet-Bonnet esthesiometer in 100 eyes from 50 healthy adult horses.
- Corneal touch threshold (CTT) was measured in five distinct corneal regions: central, nasal, temporal, ventral, and dorsal.
Main Results:
- Significant regional variations in corneal sensitivity were observed, with the dorsal region being significantly less sensitive (P < 0.0001) than the central, nasal, temporal, and ventral regions.
- While corneal sensitivity showed a slight, often insignificant, trend with age in some regions, no significant differences were found between sexes or between left and right eyes.
Conclusions:
- Reference values for corneal touch threshold (CTT) were successfully generated for healthy adult horses.
- These established reference values are vital for diagnosing and monitoring corneal sensation alterations associated with ocular or systemic diseases in horses.

