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Hide and seek: the immunology of HSV persistence
Francis R Carbone1, Peter G Speck
1Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia.
Immunity
|May 20, 2003
Abstract:
Herpes simplex virus (HSV) has been thought to persist as a latent infection by completely extinguishing antigen expression. In this issue of Immunity, Khanna et al. challenge this view by showing that CTL specific for antigens normally associated with active viral replication are crucial participants in regulating virus latency.