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[Detection of nuclear factor kappa B by immunochemical staining and image analysis]

Gui-lin Zhang1, Shang-xi Liu, Yan Deng

  • 1Department of Nephrology, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.

Di 1 Jun Yi Da Xue Xue Bao = Academic Journal of the First Medical College of PLA
|May 20, 2003
PubMed
Abstract

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The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
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