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[The epidemiology of heart failure in Japan]
Hiroshi Okamoto1, Akira Kitabatake
1Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine.
Insights
Heart failure survival in Japan has improved over 27 years, with ten-year survival rates exceeding 90% in patients treated with ACE inhibitors and beta blockers. This progress is partly due to older, less severely affected patients and better treatments.
Area of Science:
- Cardiology
- Epidemiology
- Public Health
Context:
- Heart failure (HF) poses a significant public health challenge in Japan, with an estimated one million individuals affected.
- Limited epidemiological data exist on HF prognosis and survival trends in a Japanese population-based setting.
- Dilated cardiomyopathy (DCM) is a primary cause of severe heart failure.
Purpose:
- To investigate temporal changes in heart failure prognosis and survival over 27 years in Japan.
- To analyze survival rates across three distinct 9-year periods.
- To identify factors influencing survival improvements in heart failure patients.
Summary:
- A 27-year study analyzed three cohorts, revealing progressive improvements in 10-year heart failure survival rates.
- Patients in later cohorts were older and less severely affected, contributing to improved survival.
- Subgroup analysis showed that 10-year survival rates exceeded 90% for patients treated with ACE inhibitors and beta blockers.
Impact:
- Demonstrates significant advancements in heart failure management and patient outcomes in Japan.
- Highlights the effectiveness of ACE inhibitors and beta blockers in improving long-term survival.
- Provides crucial epidemiological insights for public health strategies and future research in heart failure.
Abstract:
Very limited epidemiological data are available regarding the prognosis of heart failure and temporal changes in survival in a population-based setting in Japan. It is estimated from the total sales of digitalis, its prescription rate and usage ratio for arrhythmias that at least one million of patients suffer from heart failure in Japan. Dilated cardiomyopathy (DCM) is a major cause of severe heart failure. Over the past 27 years, three cohorts corresponding to three different periods of 9 years were investigated. Ten-year survivals were progressively improved. Patients were older and less severely affected, partly explaining the improvement in survival. In the subgroups treated with ACE inhibitors and beta blockers, calculated ten-year survival rate reached over 90%.
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