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Vitamin A supplementation on child morbidity
J Haidar1, D Tsegaye, D H Mariam
1Ethiopian Health and Nutrition Research Institute, Addis Ababa, Ethiopia.
Insights
Vitamin A supplementation significantly reduced child morbidity and improved nutritional status in Ethiopia. This intervention highlights the importance of vitamin A for child health and development.
Area of Science:
- Public Health
- Nutrition Science
- Pediatrics
Background:
- Childhood morbidity and malnutrition are significant public health concerns in developing regions.
- Vitamin A deficiency is a leading cause of preventable childhood blindness and increases the risk of severe illness and death.
Purpose of the Study:
- To evaluate the impact of vitamin A supplementation on child morbidity and nutritional status.
- To assess changes in xerophthalmia, clinical morbidity, and serum retinol levels following intervention.
Main Methods:
- A community-based interventional study was conducted in two districts of Tigray, North Ethiopia.
- 4,770 children (6-72 months) were assessed for clinical outcomes, with a sub-sample (n=281) analyzed for serum retinol levels before and after vitamin A supplementation.
Main Results:
- Vitamin A capsule coverage reached 87%, leading to significant reductions in xerophthalmia (Bitot's spot), fever, diarrhea, measles, conjunctivitis, and edema.
- Improvements were observed in nutritional status indicators, including reduced stunting, wasting, and underweight prevalence.
- Normal serum retinol levels increased significantly from 36.8% to 56.2% post-intervention.
Conclusions:
- Vitamin A supplementation demonstrated a significant positive impact on reducing child morbidity and improving nutritional status.
- The findings underscore the effectiveness of vitamin A supplementation programs in vulnerable populations.
- Integrating nutrition education with vitamin A supplementation is recommended for sustained health benefits.
Objective:
To determine the impact of vitamin A supplementation on child morbidity and nutritional status.
Design:
A community based follow-up (interventional) in nature.
Setting:
Two randomly selected Weredas (districts) of Tigray, North Ethiopia were studied between 1996 and 1997.
Subjects:
Four thousand seven hundred and seventy children aged between six and 72 months, selected using a multi-stage sampling procedure were enrolled and clinically assessed for xerophthalmia and nutritional status. A sub-sample of these children (n = 281) was further assessed for their serum retinol levels.
Main Outcome Measures:
The pre and post intervention data on xerophthalmia, morbidity, nutritional status and serum retinol levels were compared.
Results:
Vitamin A capsule coverage of 87% in all the villages of the Weredas and a statistically significant (p < 0.05) reduction in the prevalence of Bitot's spot (from 1.5 to 0.5), fever (from 29.8 to 14.2), diarrhoea (from 30.2 to 18.2), oedema (from 9.2 to 3.2), measles (from 14.0 to 6.2), conjunctivitis (from 10.2 to 3.0), stunted (from 64.2 to 42.7), wasted (from 12.8 to 2.5) and underweight (from 46.2 to 24.2). The proportion of children with normal serum retinol concentration (> 0.7 micromole/L) has also improved significantly (from 36.8 to 56.2).
Conclusion:
In conclusion, the significant improvement in morbidity and nutritional status that followed the intervention programme although encouraging, it still indicates the importance of coupling periodic provision of Vitamin A capsules with nutrition education.
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