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Related Experiment Videos

[Cellular immunity in melanomalignome (author's transl)].

J Fritz, K Grond, G P Tilz

    Archives for Dermatological Research = Archiv Fur Dermatologische Forschung
    |April 21, 1976
    PubMed
    Summary

    Patients with melanoma malignoma exhibit cellular immunity against melanoma-associated antigens, regardless of disease stage, as shown by the Leukocyte-Migration-Inhibition-Test.

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    Assessment of the Clinical Impact of a Liver-Specific, BCAA-Enriched Diet in Major Liver Surgery.

    Transplantation proceedings·2020

    Area of Science:

    • Immunology
    • Oncology
    • Cellular Biology

    Context:

    • Melanoma malignoma is a significant health concern.
    • Understanding cellular immunological reactivity in cancer patients is crucial for developing effective treatments.
    • Previous research has explored tumor-associated antigens in various cancers.

    Purpose:

    • To investigate the cellular immunological reactivity in patients with melanoma malignoma.
    • To determine if melanoma-associated antigens are present in tumor extracts.
    • To assess the correlation between cellular immunity and clinical stages of melanoma malignoma.

    Summary:

    • Cellular immunological reactivity was assessed in 20 melanoma malignoma patients using the Leukocyte-Migration-Inhibition-Test and homologous melanoma extracts.
    • Cell migration inhibition was observed in 15 out of 20 patients, indicating the presence of melanoma-associated antigens.
    • Cellular immunity against these tumor antigens was present irrespective of the clinical stage of the disease.

    Impact:

    • This study demonstrates that melanoma patients generate cellular immunity against melanoma-associated antigens.
    • The findings suggest that tumor extracts contain relevant antigens for immune response.
    • The research indicates that immune mechanisms may not directly influence the clinical course of melanoma malignoma.

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