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[A brief outline of the evolution of lymphoid tissue and its immunocellular reactivity in vertebrates]

Arkhiv Anatomii, Gistologii I Embriologii
|March 1, 1976
PubMed

The steps of the phylogenetic development of the lymphoid tissue and its immunolcellular reactivity were studied. It was shown that a gradual change from lymphoid multifunctional cells disposed diffusely in primitive lower vertebrates to the concentration of lymphoid cells into complicatedly arranged lymph nodes was taking place. Common features and species (group) peculiarities of the structure of the lymphoid tissue and its immunological reactivity were studied. The similar succession of immunocellular reactions has the phagocyte reaction as the first link. Then goes the lymphocyte reaction with a following transformation of lymphocytes to blasts and their further differentiation and proliferation into young forms of cells of the plasmocyte row. The antibody-forming cells were found in all the vertebrates studied and their morphology was under research. Species peculiarities of lymphoid cells and their immunoreactivity were studied.

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