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Fifty years at Framingham: contributions to stroke epidemiology

Philip A Wolf1

  • 1Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.

Advances in Neurology
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A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...