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Stability and antibacterial activity of cefepime during continuous infusion
Pål F Sprauten1, Paul M Beringer, Stan G Louie
1University of Oslo, Oslo, Norway.
Antimicrobial Agents and Chemotherapy
|May 23, 2003
Abstract:
The stability of cefepime during simulated continuous infusion was determined with a motorized portable infusion pump worn over a period of 24 to 36 h. Susceptibility testing on cefepime solutions over time indicates that the degradation products do not exhibit antibacterial activity. Cefepime stability at 24 h following continuous infusion was 94.3% +/- 1.0%, which supports the use of continuous infusion.