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Updated: Aug 8, 2026

Isolation and Quantitative Evaluation of Brush Cells from Mouse Tracheas
Published on: June 12, 2019
[Roles of CD43, CD20 and local IgE in the pathogenesis of nasal polyps]
1Beijing Institute of Otorhinolaryngology, Beijing 100005, China. wangxiangdong88@sina.com
Objective:
To estimate the roles of CD43, CD20 and total IgE in the pathogenesis of nasal polyps.
Method:
Twenty-six cases of nasal polyps and 20 cases of mucosa of middle turbinates were used in present study.
Results:
The number of CD43+ cells, CD20+ cells and plasma cells in nasal polyps were significantly more than that in middle turbinates (P < 0.01). The positive rate of local IgE+ cells in nasal polyps was significantly higher than in middle turbinate (P < 0.01).
Conclusion:
There were active cellular immunity and humoral immunity in nasal polyps. Local allergy may play a role in the pathogenesis of nasal polyps.
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