Related Experiment Video
Updated: Aug 19, 2026

Whole-mount Imaging of Mouse Embryo Sensory Axon Projections
Published on: December 9, 2014
[Effect of transduction bax gene on experimental nasopharyngeal carcinoma]
1Department of Otorhinolaryngology, Third Hospital of Sun-Yat-Sen University of Medical Sciences, Guangzhou 510630, China. lhb73@263.net
Objective:
To evaluate the effect of transduction bax gene on nasopharyngeal carcinoma (NPC).
Methods:
The transduced bax gene was mediated by Dosper lipidsome to the HNE-1 cell lines, and confirmed by immunofluorescent stain. The apoptosis of the cell lines was studied by MTT stain and flow cytometry and the growth of implanted tumor in naked mouse after local injection of bax geneobserved.
Results:
Instantaneous expression of bax gene in HNE1 cell lines was testified by immunofluorescent stain after transduction for 48 hours, the apoptotic index were 10.7% and 69.4% for pre- and post-transduction, respectively. MTT stain showed the values of A in 490 nm after transduction to be 2.004(36 h) and 1.902(48 h). The diameter of implanted tumor mass was (1.8 +/- 0.64) cm and (3.0 +/- 0.44) cm in experimental and control groups, respectively.
Conclusion:
The transduction bax gene can enhance the apoptosis of HNE1 cell lines and prevent growth of implanted tumor.
More Related Videos
08:51Applying an Inducible Expression System to Study Interference of Bacterial Virulence Factors with Intracellular Signaling
Published on: June 25, 2015
09:03Identification and Characterization of Metastatic Factors by Gene Transfer into the Novel RIP-Tag; RIP-tva Murine Model
Published on: October 16, 2017
Related Concept Videos
NF-κB-dependent Signaling Pathway
NF-κB-dependent Signaling Mechanism
The heterodimer of NF-κB...
The Ras Gene
Ras is a superfamily...