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[Association between chronic gastritis in childhood, Helicobacter pylori and ABO blood groups]

Esad Brigić1, Selma Terzić, Ermina Iljazović

  • 1Pedijatrijska klinika UKC Tuzla.

Medicinski Arhiv
|May 24, 2003
PubMed

Insights

This study investigated the link between chronic gastritis, Helicobacter pylori infection, and ABO blood groups in children. Blood groups A and O were found to be more prevalent in children with gastritis, particularly those with H. pylori infection.

Area of Science:

  • Pediatric Gastroenterology
  • Immunogenetics

Background:

  • Gastritis, an inflammation of the gastric lining, has multiple causes, with Helicobacter pylori infection being the most common.
  • The association between ABO blood groups and various diseases is an area of ongoing research, with limited understanding for conditions beyond hemolytic disease of the newborn.

Purpose of the Study:

  • To explore the relationship between chronic gastritis in childhood, Helicobacter pylori infection status, and ABO blood group phenotypes.

Main Methods:

  • A cohort of 68 pediatric patients was analyzed.
  • Patients were tested for Helicobacter pylori infection.
  • ABO blood group phenotyping was performed.

Main Results:

  • Out of 68 patients, 57 (83%) were positive for Helicobacter pylori (Hp+).
  • Thirty patients were diagnosed with chronic gastritis, of whom 22 (73%) were Hp+ and 8 (27%) were Hp-.
  • Blood groups A and O showed a higher prevalence among patients with gastritis compared to other blood groups.

Conclusions:

  • The findings suggest a potential association between ABO blood groups, specifically A and O, and the occurrence of chronic gastritis in children.
  • Helicobacter pylori infection is a significant factor in childhood gastritis, and its interaction with blood groups warrants further investigation.

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