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Clinics in diagnostic imaging (81). Hypothalamic glioma with diencephalic syndrome

P Visrutaratna1, K Oranratanachai

  • 1Department of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand. pvisruta@mail.med.cmu.ac.th

Singapore Medical Journal
|May 24, 2003
PubMed

Insights

A pediatric patient presented with failure to thrive due to a suprasellar mass, diagnosed as juvenile pilocytic astrocytoma. This case highlights imaging characteristics and differential diagnoses for pediatric diencephalic syndrome.

Area of Science:

  • Pediatric Oncology
  • Pediatric Neurosurgery
  • Pediatric Radiology

Background:

  • Diencephalic syndrome in infants is characterized by failure to thrive, often caused by a suprasellar mass.
  • Early diagnosis and intervention are crucial for managing pediatric diencephalic syndrome.

Observation:

  • A 15-month-old boy presented with failure to thrive and third-degree malnutrition.
  • MR imaging revealed a large, lobulated suprasellar mass with specific signal characteristics (hypointense on T1, hyperintense on PD/T2, homogeneous enhancement).

Findings:

  • Histopathological examination confirmed the suprasellar mass as a juvenile pilocytic astrocytoma.
  • The tumor was identified as the cause of the patient's diencephalic syndrome.

Implications:

  • This case underscores the importance of comprehensive imaging and histopathological analysis for diagnosing suprasellar masses in children.
  • Understanding the imaging features of juvenile pilocytic astrocytoma aids in differentiating it from other suprasellar pathologies in pediatric patients.

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