Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Iodine excess and thyroid autoimmunity.

C Bournaud1, J J Orgiazzi

  • 1Service d'Endocrinologie, Diabétologie et Maladies Métaboliques, Centre Hospitalier Lyon-Sud, 69495 Pierre-Bénite Cedex, France.

Journal of Endocrinological Investigation
|May 24, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Does early response to intravenous glucocorticoids predict the final outcome in patients with moderate-to-severe and active Graves' orbitopathy?

Journal of endocrinological investigation·2017
Same author

[Benign struma ovarii: Report of 7 cases and review of the literature].

Gynecologie, obstetrique & fertilite·2016
Same author

Follow-up of differentiated thyroid carcinoma.

Annales d'endocrinologie·2016
Same author

Efficacy and safety of three different cumulative doses of intravenous methylprednisolone for moderate to severe and active Graves' orbitopathy.

The Journal of clinical endocrinology and metabolism·2012
Same author

(18)F-FDG uptake at initial staging of the adrenocortical cancers: a diagnostic tool but not of prognostic value.

World journal of surgery·2012
Same author

Assessment of the incremental value of recombinant thyrotropin stimulation before 2-[18F]-Fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography imaging to localize residual differentiated thyroid cancer.

The Journal of clinical endocrinology and metabolism·2009
Same journal

Delirium in diabetic ketoacidosis: a multicenter observational study of occurrence, associated factors and outcomes from 578,204 hospitalizations.

Journal of endocrinological investigation·2026
Same journal

Low work ability and high disability burden in Cushing's syndrome: a multicenter cohort study.

Journal of endocrinological investigation·2026
Same journal

Association of C-reactive protein to albumin ratio with progression of CKD and all-cause mortality in diabetic CKD.

Journal of endocrinological investigation·2026
Same journal

PMOS in black girls and women: from high to low risk.

Journal of endocrinological investigation·2026
Same journal

Inhibition of TGF-β1/Smad signaling reverses the dedifferentiated phenotype of thyroid cancer cells in three-dimensional culture.

Journal of endocrinological investigation·2026
Same journal

lncRNA PANDAR predicts adverse pregnancy outcomes and reflects hyperglycemia-associated cellular stress in gestational diabetes mellitus.

Journal of endocrinological investigation·2026
See all related articles

Iodine may trigger thyroid autoimmunity in susceptible individuals. Despite increased autoimmune thyroid disease in iodine-sufficient areas, iodine prophylaxis remains crucial for public health.

Area of Science:

  • Endocrinology
  • Immunology
  • Public Health

Background:

  • Iodine's role in thyroid health is complex.
  • Studies suggest iodine can be immunogenic, potentially triggering thyroid autoimmunity in predisposed individuals.

Purpose of the Study:

  • To review epidemiological and experimental data on iodine's impact on thyroid autoimmunity.
  • To assess the relationship between iodine intake and autoimmune thyroid diseases across various populations and conditions.

Main Methods:

  • Analysis of epidemiological data from diverse populations with varying iodine statuses (deficient, sufficient, excessive).
  • Review of experimental studies involving iodine prophylaxis and supplementation (iodide, iodized oil).
  • Examination of data from general populations, euthyroid goiter, autoimmune goiter, and postpartum thyroid disease cohorts.

Related Experiment Videos

Main Results:

  • Evidence suggests iodine can act as an immunogen for the thyroid gland, particularly in susceptible subjects.
  • Autoimmune thyroid diseases have increased in iodine-sufficient areas.
  • Data were analyzed under conditions of stable iodine deficiency, sufficiency, excess, and during iodine supplementation.

Conclusions:

  • The rise in autoimmune thyroid diseases in iodine-sufficient regions should not halt iodine prophylaxis initiatives.
  • Iodine prophylaxis remains a vital public health strategy despite potential immunogenic effects in specific contexts.