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Multivalent neoglycoconjugates by regiospecific cycloaddition of alkynes and azides using organic-soluble copper
Francisco Pérez-Balderas1, Mariano Ortega-Muñoz, Julia Morales-Sanfrutos
1Instituto de Biotecnología, Facultad de Ciencias, Universidad de Granada, E-18071 Granada, Spain.
Organic Letters
|May 24, 2003
Abstract:
[reaction: see text] The construction of multivalent neoglycoconjugates is efficiently achieved by the regiospecific catalytic cycloaddition of alkynes and azides using the organic-soluble copper complexes (Ph(3)P)(3).CuBr and (EtO)(3)P.CuI. The simultaneous use of microwave irradiation shortened notably the reaction times.