Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A Cartesian coordinate system for human cerebral cortex.

David F Li1, Alan W Freeman, Hoang Tran-Dinh

  • 1School of Biomedical Sciences, University of Sydney, PO Box 170, NSW 1825, Lidcombe, Australia.

Journal of Neuroscience Methods
|May 24, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Chronological age and biological maturity are separately positively associated with inhibitory control and working memory in boys and girls.

Frontiers in cognition·2026
Same author

Making neural networks more neural.

Patterns (New York, N.Y.)·2026
Same author

Influence of aerobic fitness status on the power output decrement during repeated sprint running in females.

The Journal of sports medicine and physical fitness·2025
Same author

Longitudinal development of match performance in elite field hockey players training within a high-performance environment.

Journal of sports sciences·2025
Same author

The receptive field construction of midget ganglion cells in primate retina.

Journal of neurophysiology·2024
Same author

Changes in the ideal body shape associated with adolescent rowing-ergometry performance following a 6-week training intervention: New scaling insights using three-dimensional allometry.

European journal of sport science·2024
Same journal

Detection of cochlear microphonic for differential diagnosis between auditory neuropathy mice and noise-induced sensorineural hearing loss mice.

Journal of neuroscience methods·2026
Same journal

Assessment metrics for pain control in rats: A methodological commentary.

Journal of neuroscience methods·2026
Same journal

Infant EEG preprocessing pipelines: A capability framework and current gaps in practice.

Journal of neuroscience methods·2026
Same journal

Methods for measuring neural activity during voluntary wheel running.

Journal of neuroscience methods·2026
Same journal

Serotype-dependent differences in AAV cellular transduction rates in the hypothalamus of Arctic ground squirrels.

Journal of neuroscience methods·2026
Same journal

Rapid generation of human sensory neurons from iPSC for modeling of peripheral neuropathies.

Journal of neuroscience methods·2026
See all related articles

A new Sydney coordinate system improves human cerebral cortex mapping by addressing limitations in the Talairach system. It offers a longer, more identifiable axis and normalizes for brain size, enhancing precision for functional area localization.

Area of Science:

  • Neuroimaging
  • Neuroanatomy
  • Medical Imaging

Background:

  • The Talairach coordinate system is widely used for localizing functional areas in the human cerebral cortex.
  • This system faces challenges with posterior commissure identification, axis length, and brain size normalization.
  • These limitations impact the accuracy of cortical localization.

Purpose of the Study:

  • To introduce and validate the Sydney coordinate system as an improvement over the Talairach system for cortical mapping.
  • To address the identified limitations of the Talairach system for precise anatomical localization.

Main Methods:

  • Developed the Sydney system with a longer fundamental axis from the corpus callosum to the parieto-occipital sulcus.
  • Implemented normalization by dividing distances by the fundamental axis length.

Related Experiment Videos

  • Measured 3D coordinates using anatomical landmarks on cadavers and MRI scans in both systems.

    • Main Results:

    • The Sydney system's fundamental axis is over four times longer and easier to identify than Talairach's.
    • The Sydney system demonstrates increased precision, reducing point scatter in measurements.
    • Normalized coordinates in the Sydney system facilitate cross-individual comparisons irrespective of brain size.

    Conclusions:

    • The Sydney coordinate system offers significant advantages for mapping functional areas in the human cerebral cortex.
    • It provides enhanced precision and normalization capabilities compared to the Talairach system.
    • The Sydney system represents a potential advancement for neuroimaging research and clinical applications.