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Advances in B-cell epitope analysis of autoantigens in connective tissue diseases

M Mahler1, M Blüthner, K M Pollard

  • 1Institute of Molecular Genetics, University of Heidelberg, Heidelberg, Germany. m.mahler.job@web.de <m.mahler.job@web.de>

Clinical Immunology (Orlando, Fla.)
|May 24, 2003
PubMed

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Antigens Involved in Adaptive Immunity

An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
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Autoimmune Disorders

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The immune system...