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Related Experiment Videos

[Memory effect of resorbable polymers].

A Patyk1, B Wollschläger, H A Merten

  • 1Abteilung Prothetik (Werkstoffkundelabor), Zentrum ZMK, Georg-August-Universität Göttingen. ajpatyk@med.uni-goettingen.de

Mund-, Kiefer- Und Gesichtschirurgie : MKG
|May 24, 2003
PubMed
Summary

Resorbable polymers used in bone fracture fixation exhibit a "memory effect," reverting to their original shape at body temperature. This effect is influenced by deformation, geometry, and polymer type, potentially impacting medical treatments.

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Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Orthopedic Surgery

Background:

  • Resorbable polymers are utilized for bone fracture stabilization, offering thermoplastic deformation for precise anatomical reconstruction.
  • Unlike metal implants, these biodegradable materials can revert to their original shape at body temperature, a phenomenon known as the 'memory effect'.
  • This inherent memory effect in resorbable polymers may lead to adverse outcomes in clinical applications.

Purpose of the Study:

  • To investigate the memory effect in resorbable polymers used for bone fracture fixation.
  • To understand how factors like temperature, deformation, geometry, and chemical composition influence this memory effect.
  • To assess the potential clinical implications of the memory effect in biodegradable orthopedic implants.

Main Methods:

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  • Specimens of polyglycolides and polylactides were prepared using compression molding.
  • Specimens were heated to 50°C, deformed to specific angles, and then placed in a 37°C water bath to simulate body temperature.
  • The degree of retroflexion, indicating the memory effect, was quantified using an XY-measuring desk.

Main Results:

  • Highly deformed specimens exhibited more pronounced retroflexion, indicating a stronger memory effect.
  • The memory effect was found to be dependent on both the geometrical design of the specimens and their chemical composition.
  • All tested polymers demonstrated an initial strong memory effect that diminished over time.

Conclusions:

  • The memory effect in resorbable polymers is a significant factor in their orthopedic applications.
  • Understanding the variables influencing this effect is crucial for optimizing the design and use of biodegradable implants.
  • Further research is needed to mitigate negative consequences and fully leverage the benefits of resorbable polymers in fracture fixation.