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Updated: Sep 13, 2026
Quantification of Tumor Cell Adhesion in Lymph Node Cryosections
Published on: February 9, 2020
[A clinical and pathological study on cervical lymph node metastasis in the clinical N0 patient with laryngeal
1Department of Head ard Neck Surgery, Third Affiliated Hospital, Harbin Medical University, Harbin 150040.
Objective:
To study the characteristics of the cervical lymph node metastasis in negative nodes (N0) with clinically with laryngeal carcinoma patients and its implication in clinical treatment.
Methods:
Forty patients with laryngeal carcinomas of No category were divided randomly into two groups: 13 radical neck dissections (RND) and 27 functional neck dissections (FND) were performed. Lymph nodes were studied histologically.
Results:
On an average, 34.2 lymph nodes were obtained in one side of neck in RND group, and 27.4 in FND group (t = 0.86, P > 0.05). The metastases rates were 30.8% (4/13) in RND group and 33.3% (9/27) in FND group, and the total metastasis rate was 32.5% (13/40). Twelve of 13 patients (92.3%) who had positive nodes involved only the levels II and III, and 32 of 33 positive nodes (96.9%) were located in the levels II and III. The 3-year survival rates of the two groups were 69.2% (9/13) and 77.8% (21/17), respectively with no statistical difference (chi 2 = 0.3418, P > 0.5). Total 3-year survival rate was 75% (30/40).
Conclusion:
The supraomohyoid (level Io II and III) or lateral neck (level II, III and IV) dissections seem suitable for the treatment laryngeal carcinoma patients with clinically negative neck nodes.
