Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Advanced Dynamic Flow]

Takeshi Sato1

  • 1Ultrasound Systems Development Department Medical Systems Company, Toshiba Corporation. takeshi.sato@toshiba.co.jp

Igaku Butsuri : Nihon Igaku Butsuri Gakkai Kikanshi = Japanese Journal of Medical Physics : an Official Journal of Japan Society of Medical Physics
|May 27, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of ensemble averaging on Green-Kubo estimation of short-time stress relaxation modulus in all-atom molecular dynamics simulations of an unentangled polymer melt.

The Journal of chemical physics·2026
Same author

SLIDE: Quantifying Transmembrane Protein Interface Specificity through Persistence Score and Friction Energy.

Journal of chemical information and modeling·2026
Same author

Arterial Perfusion Changes Following Transcatheter Arterial Microembolization for Hand Joint Pain.

Cardiovascular and interventional radiology·2026
Same author

Innovation of a Repeatable Microcatheter-accessible Port (ReMAP): Initial Clinical Results Evaluating Feasibility in the Treatment of Hepatocellular Carcinoma.

Interventional radiology (Higashimatsuyama-shi (Japan)·2026
Same author

Modeling human prenatal adrenocortical functional zonation dynamics from pluripotent stem cells.

Cell stem cell·2026
Same author

Coherent control of electron-ion entanglement in multiphoton ionization.

Light, science & applications·2026
Same journal

[Report of the 129th Scientific Meeting of Japan Society of Medical Physics].

Igaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics·2026
Same journal

[RPT Doi Award: A novel internal target volume definition based on velocity and time of respiratory target motion for external beam radiotherapy].

Igaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics·2026
Same journal

[RPT Doi Award: Visualization of distribution in the vitreous cavity via eye drops using ultra-heavily T2-weighted sequences in MRI: a preliminary study with enucleated pig eyes].

Igaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics·2026
Same journal

[RPT Doi Award: Deep learning-based correction for time truncation in cerebral computed tomography perfusion].

Igaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics·2026
Same journal

[EDITOR'S NOTE].

Igaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics·2026
Same journal

[Medical Physicist-Patient Communication and Advocacy in Radiation Therapy - Insights from AAPM Task Group No. 422].

Igaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics·2026
See all related articles

Dynamic Flow imaging overcomes limitations of conventional contrast imaging with Levovist. Advanced Dynamic Flow (ADF) offers superior resolution, reduced blooming, and enhanced bubble detectability for clearer visualization.

Area of Science:

  • Medical Imaging
  • Ultrasound Technology
  • Contrast-Enhanced Ultrasound

Background:

  • Conventional Doppler, 2nd harmonic imaging, and pulse inversion imaging face challenges with Levovist contrast agent.
  • High mechanical index (MI) required for Levovist leads to poor resolution, blooming, and tissue harmonic interference (THI).
  • Bubble collapse under high MI hinders continuous visualization of Levovist microbubbles.

Purpose of the Study:

  • To introduce and evaluate Dynamic Flow and Advanced Dynamic Flow (ADF) imaging techniques for contrast imaging with Levovist.
  • To address the limitations of existing ultrasound modes in visualizing Levovist microbubbles.
  • To enhance the sensitivity, resolution, and detectability of microbubbles in ultrasound contrast imaging.

Main Methods:

Related Experiment Videos

  • Dynamic Flow imaging utilizes Doppler principles with improved resolution and reduced blooming.
  • Advanced Dynamic Flow (ADF) further enhances sensitivity and presentation capabilities.
  • Evaluation of bubble detectability, penetration, and image quality in various vessel sizes and depths.
  • Main Results:

    • Dynamic Flow provides higher resolution and less blooming compared to conventional Doppler.
    • ADF offers superior bubble detectability, comparable to B-mode imaging, with enhanced penetration and uniform enhancement.
    • ADF effectively visualizes microbubbles in smaller vessels and maintains high frame rates.

    Conclusions:

    • Dynamic Flow and ADF significantly improve ultrasound contrast imaging with Levovist.
    • ADF provides excellent visualization of microbubbles, even in small vessels, with improved penetration.
    • ADF is highly suitable for Levovist contrast imaging and can also be used for non-contrast imaging of small vessels.