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Updated: Aug 4, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
Published on: October 20, 2016
Does a prolonged QT peak identify left ventricular hypertrophy in hypertension?
K Y K Wong1, P O Lim, S Y S Wong
1The Cardiovascular Research Group, Ninewells Hospital, Dundee, UK. kywong@doctors.org.uk <kywong@doctors.org.uk>
Measuring QT peak on an ECG may be a cost-effective method for identifying patients with left ventricular hypertrophy. This approach shows promise in detecting cardiac conditions in hypertensive individuals.
Area of Science:
- Cardiology
- Diagnostic Imaging
- Hypertension Management
Background:
- Left ventricular hypertrophy (LVH) is a significant predictor of mortality.
- Increased QT (end) dispersion in hypertensive patients with LVH is linked to cardiac death.
- QT (end) dispersion is underutilized despite its prognostic importance.
Purpose of the Study:
- To test the hypothesis that a prolonged QT peak is associated with LVH.
- To assess the cost-effectiveness of QT peak measurement for diagnosing LVH.
Main Methods:
- ECGs and echocardiograms were analyzed in 47 hypertensive patients.
- QT peak (start of QRS to peak of T wave) was measured from lead I of ECGs.
- Receiver-operator characteristic curves determined sensitivity and specificity of QT peak for predicting LVH.
Main Results:
- Heart-rate corrected QT peak correlated with left ventricular mass index (r=0.45, P=0.002).
- A prolonged QT peak (> or =300 ms) demonstrated 100% sensitivity for detecting LVH.
- QT peak measurement was more cost-effective than Sokolow-Lyon voltage criteria.
Conclusions:
- QT peak measurement may be a cost-effective method for identifying hypertensive patients with LVH.
- Further validation in larger studies is warranted.
- This ECG criterion offers improved diagnostic value and resource efficiency.
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