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Updated: Sep 25, 2026

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection
Published on: September 14, 2019
[Cryptosporidium infection in immunocompetent and immunocompromised host]
A. Maisto1, A.R. Sorrentino, G.B. Gaeta
1Istituto di Malattie Infettive, Seconda Universita, Napoli, Italy.
Abstract:
Prior to 1980 infections with Cryptosporidium species were considered extremely rare in humans. During the eighties, evidence cumulates that this intracellular protozoan was often responsible of self-limiting diarrheal illness in immunocompetent patients and of a prolonged, life-threatening disease in immunocompromised hosts, especially patients with AIDS. The aim of this paper is to review the present knowledge on Cryptosporidium biology, epidemiology, pathogenesis, diagnosis, therapy and highlight recent studies on the clinical aspects of this infection.
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