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Updated: Aug 1, 2026

A Novel Human Epithelial Enteroid Model of Necrotizing Enterocolitis
08:42

A Novel Human Epithelial Enteroid Model of Necrotizing Enterocolitis

Published on: April 10, 2019

Pseudomembranous and neutropenic enterocolitis in pediatric oncology patients

M D van de Wetering1, T W Kuijpers, J A J M Taminiau

  • 1Academic Medical Center, Emma Children's Hospital, Amsterdam, The Netherlands. m.d.vandewetering@amc.uva.nl

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer
|May 28, 2003
PubMed

Insights

Early diagnosis of neutropenic enterocolitis in cancer patients, including Clostridium difficile infection, improves outcomes. Understanding the pathology and immunology aids in better management and patient care.

Area of Science:

  • Gastroenterology
  • Oncology
  • Infectious Diseases

Background:

  • Neutropenic enterocolitis presents diverse clinicopathological features in cancer patients.
  • Prompt diagnosis is crucial for effective supportive care and improved patient prognosis.

Observation:

  • Case 1: A child with pseudomembranous colitis due to Clostridium difficile.
  • Case 2: A child with neutropenic enterocolitis without identified organism.

Findings:

  • Detailed analysis of pathology, immunology, and culture results is essential.
  • Early diagnosis facilitates timely and appropriate clinical management.

Implications:

  • Improved diagnostic strategies can enhance patient outcomes in neutropenic enterocolitis.
  • Further research into the diverse etiologies of neutropenic enterocolitis is warranted.

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