Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Biogenic peptides and their potential use.

Naoyuki Yamamoto1, Masahiro Ejiri, Seiichi Mizuno

  • 1R&D center, Calpis Co., Ltd., 11-10, 5-Chome, Fuchinobe, Sagamihara, Kanagawa 229, Japan. naoyuki.yamamoto@calpis.co.jp

Current Pharmaceutical Design
|May 29, 2003
PubMed
Summary

This review highlights bioactive peptides from food proteins, focusing on antihypertensive peptides. These peptides show promise for managing and preventing hypertension, offering an alternative to traditional medicines.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Randomized trial of carbonated water consumption on snacking behavior, alcohol intake, and health indices in healthy Japanese adults.

Scientific reports·2026
Same author

Launching Japan's first collaborative model for implementing shelter-in-place operations at medical institutions near nuclear power plants.

Journal of radiological protection : official journal of the Society for Radiological Protection·2026
Same author

Building neuroanatomical resources for three-spined sticklebacks: Brain areas important for social behavior.

bioRxiv : the preprint server for biology·2026
Same author

Casomorphine-10 (CM-10) Peptide Orchestrates Circadian and Neurodevelopmental Gene Clusters via δ-Opioid Receptor Signaling: Insights from Transcriptome Analysis with δ-Opioid Receptor-Expressing HEK293 Cells.

Life (Basel, Switzerland)·2025
Same author

Putative genes coding for pituitary adenylate cyclase-activating polypeptide and immunohistochemical localization of their mature peptides in the brain-pituitary axis of the inshore hagfish Eptatretus burgeri.

General and comparative endocrinology·2025
Same author

Identification of "Spinal Enlargements" Correlating with Paired and Unpaired Fins in Zebrafish.

Brain, behavior and evolution·2025

Area of Science:

  • Food Science
  • Biochemistry
  • Pharmacology

Background:

  • Food proteins can be hydrolyzed into bioactive peptides with various physiological functions.
  • Antihypertensive peptides, particularly those inhibiting angiotensin I-converting enzyme (ACE), are a significant class of these peptides.
  • These peptides are derived from diverse food sources including milk, meat, fish, cereals, legumes, and eggs, as well as fermented products.

Purpose of the Study:

  • To review the origins and types of bioactive peptides from food protein hydrolysis.
  • To extensively discuss antihypertensive peptides, their mechanisms, and sources.
  • To introduce new research findings and compare their efficacy with medicinal substances.

Main Methods:

  • Literature review of bioactive peptides from food materials and enzymatic protein hydrolysis.

Related Experiment Videos

  • Classification and detailed examination of antihypertensive peptides based on ACE inhibitory activity.
  • Summary of clinical study efficacies and comparison with conventional drugs.

    • Main Results:

    • Antihypertensive peptides are extensively reviewed, categorized into ACE inhibitory and other types.
    • Peptides derived from various food sources demonstrate significant antihypertensive effects in animal models.
    • Clinical studies indicate the potential of these peptides in hypertension management and prevention.

    Conclusions:

    • Bioactive peptides, especially antihypertensive ones, represent a promising area for nutritional intervention in hypertension.
    • Enzymatic hydrolysis of food proteins is a viable method for producing these therapeutic peptides.
    • Further research and clinical validation support the use of biogenic peptides for hypertension treatment and prevention.