Related Experiment Videos
Trends in the BVDV serological response in the Upper Midwest
Christopher C L Chase1, Stephanie K Chase, Linda Fawcett
1Department of Veterinary Science, ADRDL Building Room 125, Box 2175, South Dakota State University, Brookings, SD 57007, USA. christopher_chase@sdstate.edu
Summary
Bovine viral diarrhoea virus (BVDV) infection rates, measured by serum neutralization (SN) titres, significantly increased from 1995-2001. This rise in BVDV SN titres suggests increased field infections and vaccination impact.
Area of Science:
- Veterinary Virology
- Immunology
- Epidemiology
Background:
- Bovine viral diarrhoea (BVD) is a significant disease impacting cattle health and productivity.
- Serum neutralization (SN) assays are crucial for assessing BVD virus (BVDV) exposure and infection levels in herds.
- Understanding BVDV serological trends is vital for disease management and control strategies.
Purpose of the Study:
- To analyze trends in BVDV serum neutralization (SN) titres over a seven-year period.
- To investigate changes in antibody levels indicative of BVDV infection or vaccination.
- To evaluate the implications of serological trends for BVDV control programs.
Main Methods:
- Retrospective analysis of BVDV Type 1 and Type 2 SN assay results.
- Data collected from 1995 to 2001 at the Animal Disease Research and Diagnostic Laboratory, South Dakota State University.
- Statistical examination of titre distributions and changes over time.
Main Results:
- A progressive increase in animals with SN titres ≥512 was observed from 1995-2001, reaching 74% by 2001.
- Higher antibody titres (e.g., >4096) became more prevalent by 2001 compared to 1995.
- Significant increases in titres occurred in 1997, with titres ranging from 512-8192 remaining relatively constant from 1997-2001.
Conclusions:
- The observed rise in BVDV SN titres likely reflects increased vaccination frequency and a potential increase in field infections.
- Standardization and development of new BVDV serological methods are essential for future eradication efforts.
- Continued monitoring of BVDV seroprevalence is critical for effective herd health management.