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Related Experiment Videos

Performance indicators of organized cervical screening in Romagna (Italy).

L Bucchi1, F Falcini, P Schincaglia

  • 1Romagna Cancer Registry, Medical Oncology Department, Luigi Pierantoni Hospital, 47100 Forlì, Italy. l.bucchi@ausl.fo.it

European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)
|May 29, 2003
PubMed
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Author Correction: Oral supplementation of α-lipoic acid (ALA), magnesium, vitamin B6 and vitamin D stabilizes cervical changes in women presenting risk factors for preterm birth.

European review for medical and pharmacological sciences·2023

This study assessed the performance of an organized cervical cancer screening program in Romagna, Italy. Early results indicate acceptable performance, with a detection rate of 4.5 per 1000 participants for CIN2-3 and 0.5 for invasive carcinoma.

Area of Science:

  • Gynecologic Oncology
  • Public Health
  • Epidemiology

Background:

  • Published data on organized cervical screening programs in Southern Europe are limited.
  • This study presents findings from the first round of organized cervical screening in the Romagna region of Italy.

Purpose of the Study:

  • To evaluate the performance and early outcomes of an organized cervical cancer screening program.
  • To calculate age-specific screening performance indicators and assess detection rates for cervical intraepithelial neoplasia (CIN) and invasive carcinoma.

Main Methods:

  • A 3-yearly Pap smear screening program was implemented for women aged 25-64 years.
  • Data were collected on response rates, recall rates, cytology results, colposcopy compliance, and detection rates for CIN2-3 and invasive carcinoma.

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Main Results:

  • The total participation rate was 61.7%.
  • The recall rate was 35.2 per 1000 participants.
  • Detection rates were 4.5 per 1000 for CIN2-3 and 0.5 per 1000 for invasive carcinoma.
  • The positive predictive value for high-grade squamous intraepithelial neoplasia (HGSIL)/carcinoma was 76.5% and 100.0%, respectively.

Conclusions:

  • The organized cervical screening program in Romagna demonstrated acceptable early performance.
  • The observed to expected ratio for invasive carcinoma was 2.35, suggesting a potential impact on early detection.