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Updated: Dec 20, 2025
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Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
277
[Endoscopic intrasellar tumor surgery]
Qiuhang Zhang1, Zhili Ni, Hetai Sun
1Department of Otorhinolaryngology, Xuanwu Hospital, Capital University of the Medical Sciences, Beijing 100053, China. 67501747@sina.com.cn
Zhonghua Er Bi Yan Hou Ke Za Zhi
|May 30, 2003
Summary
Endoscopic transsphenoidal surgery is a safe and effective minimally invasive technique for removing intrasellar tumors, including pituitary adenomas and craniopharyngiomas, with good patient outcomes.
Area of Science:
- Neurosurgery
- Endocrinology
- Oncology
Context:
- Intrasellar tumors, such as pituitary adenomas, craniopharyngiomas, and meningiomas, pose surgical challenges.
- Traditional surgical approaches may involve significant morbidity.
- Endoscopic techniques offer a minimally invasive alternative for accessing the sella turcica.
Purpose:
- To evaluate the perioperative management and outcomes of endoscopic intrasellar tumor surgery.
- To assess the safety and efficacy of the endoscopic transsphenoidal approach for various intrasellar tumors.
Summary:
- Fifty-two patients with intrasellar tumors underwent endoscopic transsphenoidal surgery.
- Tumor resection rates were high, with 48/49 pituitary adenomas and 2/2 craniopharyngiomas completely removed.
- Symptomatic improvement and normalization of hormone levels (prolactin, growth hormone) were observed.
- Complications included transient/permanent diabetes insipidus and one case of epilepsy; no delayed CSF leaks, meningitis, or neurovascular injuries occurred.
- Recurrence rate was 5.8% within one year.
Impact:
- Endoscopic transsphenoidal surgery provides direct visualization and improved tumor resection.
- This minimally invasive approach is safe and efficient for managing intrasellar tumors.
- It offers a favorable alternative to traditional surgical methods, potentially reducing patient morbidity.
