Related Experiment Video
Updated: Jul 30, 2026

Visualization of DNA Replication in the Vertebrate Model System DT40 using the DNA Fiber Technique
Published on: October 27, 2011
DNA replication in the hyperthermophilic archaeon Sulfolobus solfataricus
I Dionne1, N P Robinson, A T McGeoch
1The Medical Research Council Cancer Cell Unit, Hutchison MRC Centre, Hills Road, Cambridge CB2 2XZ, UK.
Abstract:
Studies of the DNA-replication machinery of Archaea have revealed striking similarities to that of eukaryotes. Indeed, it appears that in most cases Archaea possess a simplified version of the eukaryotic replication apparatus. Studies of Archaea are therefore shedding light on the fundamental processes of DNA replication in both domains of life.
More Related Videos
Related Concept Videos
Replication in Prokaryotes
Replication in Eukaryotes
The Replisome
The synthesis of the leading and lagging strands is a highly coordinated process. To explain this, the “Trombone model” was proposed by Bruce Alberts in 1980. The DNA loop formation starts when a primer is synthesized on the parent lagging strand. The loop grows with the...
Replication in Prokaryotes
Many Proteins Work Together to Replicate the Chromosome
Replication is coordinated and carried out by a host of specialized...
Replication in Eukaryotes
Many Proteins Orchestrate Replication at the Origin
Eukaryotic replication follows many of the same...
Viruses of Archaea

