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Development, validity and responsiveness of the Clinical COPD Questionnaire
Thys van der Molen1, Brigitte W M Willemse, Siebrig Schokker
1Department of General Practice, University of Groningen, Groningen, The Netherlands. t.van.der.molen@med.rug.nl
Health and Quality of Life Outcomes
|May 30, 2003
Summary
The Clinical COPD Questionnaire (CCQ) effectively measures symptom and functional status in Chronic Obstructive Pulmonary Disease (COPD) patients. This validated tool aids in managing COPD by assessing clinical control in daily practice.
Area of Science:
- Pulmonary Medicine
- Clinical Assessment
- Health Outcomes
Background:
- Current Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines emphasize improving functional status, preventing progression, and minimizing symptoms in COPD management.
- A lack of validated questionnaires for assessing symptom and functional status in routine clinical practice hinders effective COPD management.
- The need for a reliable tool to measure clinical control in Chronic Obstructive Pulmonary Disease (COPD) patients is critical.
Purpose of the Study:
- To develop and validate the Clinical COPD Questionnaire (CCQ) for measuring clinical control in COPD patients.
- To create a user-friendly, self-administered questionnaire for daily clinical use.
- To provide a tool that aligns with GOLD guidelines for COPD management.
Main Methods:
- Qualitative research with patients and clinicians to identify key items for evaluating COPD control.
- Expert review and item reduction of a questionnaire sent to 77 international experts, with 67 responding.
- Inclusion of 10 items across three domains (symptoms, functional, and mental state) into the final CCQ.
Main Results:
- The CCQ demonstrated high internal consistency (Cronbach's alpha = 0.91) and excellent test-retest reliability (ICC = 0.94).
- CCQ scores were significantly higher in COPD patients (GOLD 0-III) compared to healthy smokers.
- Significant correlations were observed between CCQ scores and established measures like SF-36 and St. George's Respiratory Questionnaire (SGRQ), as well as FEV1%pred in COPD patients.
Conclusions:
- The Clinical COPD Questionnaire (CCQ) is a valid, reliable, and responsive self-administered tool for assessing clinical control in COPD patients.
- The CCQ is a short and easily administered questionnaire suitable for daily clinical practice.
- The study findings support the CCQ's utility in monitoring COPD patient status and treatment effectiveness.