Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Intestinal pathophysiology in autism.

John F White1

  • 1Department of Physiology, Emory University, Atlanta, Georgia 30322, USA. jfwhite@physio.emory.edu

Experimental Biology and Medicine (Maywood, N.J.)
|May 30, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Case of Caries of the Dorsal Vertebræ, with an Abscess Communicating with the Lungs, and Expectoration of Bone.

Medical examiner (Philadelphia, Pa.)·2023
Same author

On the Potential Insurability of HIV.

Journal of insurance medicine (New York, N.Y.)·2016
Same journal

Nicotinamide adenine dinucleotide phosphate oxidase 4 in lung disease: a review of its biology and therapeutic potential.

Experimental biology and medicine (Maywood, N.J.)·2026
Same journal

Phenotypic profiling of Pathogen Box compounds MMV667494 and MMV028694 in bloodstream-form <i>Trypanosoma brucei brucei</i>.

Experimental biology and medicine (Maywood, N.J.)·2026
Same journal

High systolic blood pressure and stroke: evidence from the NHANES 1999-2023 and global burden of disease 2021.

Experimental biology and medicine (Maywood, N.J.)·2026
Same journal

Scaling human liver microphysiological systems: implementing a higher-throughput liver acinus microphysiological system platform.

Experimental biology and medicine (Maywood, N.J.)·2026
Same journal

Race, oxygen exposure, and retinopathy of prematurity: re-examining a persistent epidemiologic paradox.

Experimental biology and medicine (Maywood, N.J.)·2026
Same journal

Peripheral immune cells and glycation indices as potential diagnostic biomarkers in amyotrophic lateral sclerosis.

Experimental biology and medicine (Maywood, N.J.)·2026
See all related articles

Gastrointestinal issues, including a "leaky gut," are increasingly found in children with autism spectrum disorder (ASD). Research explores how these gut problems may influence ASD symptoms and brain function.

Area of Science:

  • Neuroscience
  • Gastroenterology
  • Developmental Pediatrics

Background:

  • Autism spectrum disorder (ASD) is a complex developmental disorder with largely unknown causes.
  • Emerging research indicates significant gastrointestinal (GI) tract pathology in children with ASD.
  • This pathology spans from the esophagus to the colon.

Purpose of the Study:

  • To describe observed GI pathology in autistic children.
  • To review evidence connecting diet and ASD symptom severity.
  • To examine impaired intestinal permeability (leaky gut) in ASD and its potential influence on brain function.

Main Methods:

  • Review of recent research on GI pathology in autism.
  • Analysis of studies linking diet to ASD symptom severity.

Related Experiment Videos

  • Examination of evidence for impaired intestinal permeability in ASD.
  • Discussion of theories on leaky gut development.
  • Exploration of potential mechanisms linking GI dysfunction to brain function.

    • Main Results:

    • Pathology identified throughout the GI tract in autistic children.
    • Evidence suggests a correlation between diet and the severity of ASD symptoms.
    • Impaired intestinal permeability (leaky gut) is a noted feature in ASD.
    • Various theories explain the development of leaky gut in this population.

    Conclusions:

    • GI tract pathology is a significant finding in autism spectrum disorder.
    • Dietary interventions may play a role in managing ASD symptoms.
    • Impaired intestinal permeability may be a contributing factor to the neurological aspects of ASD.