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[Osteoporosis in the elderly man].

J-M Kaufman1

  • 1Département d'Endocrinologie et Unité d'Ostéoporose et Métabolisme Osseux, Hôpital Universitaire de Gand, De Pintelaan 185 B-9000 Gand, Belgique.

Annales D'Endocrinologie
|May 30, 2003
PubMed
Summary

Elderly men face significant fracture risks, with osteoporosis complications being more severe than in women. Prevention and treatment should address risk factors like bone density and falls, with hormonal balance being key.

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Area of Science:

  • Gerontology
  • Endocrinology
  • Orthopedics

Context:

  • Elderly men have a high risk of osteoporotic fractures, with greater morbidity and mortality compared to women.
  • Risk factors for fractures in men resemble those in women, with low bone mineral density (BMD) being a significant predictor.
  • Understanding the mechanisms of age-related bone loss and osteoporosis in men, particularly the role of hormones, requires further investigation.

Purpose:

  • To review the current understanding of osteoporotic fracture risk factors in elderly men.
  • To clarify the relationship between bone mineral density, bone geometry, and fracture risk in this demographic.
  • To explore the impact of hormonal status on skeletal homeostasis and bone metabolism in elderly men.

Summary:

  • Low bone mineral density is a key risk factor for fractures in men, though the interplay with bone geometry needs more research.
  • Hormonal factors, including testosterone and estrogens, play a role in regulating bone metabolism in elderly men.
  • Prevention strategies should focus on mitigating risk factors for bone loss and falls. Testosterone therapy is indicated only for men with pre-existing low testosterone levels.

Impact:

  • Highlights the need for further research into the pathogenesis of osteoporosis in men and the specific effects of hormonal changes.
  • Emphasizes the importance of personalized treatment approaches, particularly regarding hormonal therapy and fall prevention.
  • Calls for prospective clinical trials in elderly men, focusing on fracture incidence, to guide future treatment recommendations.

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