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Murine Full-thickness Skin Transplantation
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Zigzag seams for the prevention of scar bands after sheet split-thickness skin grafting

David G Greenhalgh1, Tina L Palmieri

  • 1Burn Surgery Department, Shriners Hospitals for Children Northern California, Sacramento, 95817, USA.

Surgery
|May 30, 2003
PubMed
Abstract

No abstract available in PubMed .

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...

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