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Updated: Sep 25, 2026

Analysis of Fatty Acid Content and Composition in Microalgae
Published on: October 1, 2013
[Studies on the chemical constituents from marine brown alga Ishige okamurai (3)]
Hai-feng Tang1, Yang-hua Yi, Xin-sheng Yao
1Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University, Shanghai 200433, China. haifengtang@hotmail.com
Objective:
To study the chemical constituents of Ishige okamurai.
Method:
Compounds were isolated by Pyricularia oryzae bioassay-guided fractionation method in combination with extraction and partitionation as well as multi-chromatography. Their structures were determined by spectral analysis and chemical evidence.
Result:
Seven compounds were obtained and identified as (2S)-1-O-palmitoyl-2-O-(11Z-octadecenoyl)-3-O-beta-D-galacto-pyranosyl glycerol (I), (2S)-1-O-palmitoyl-2-O-myristoyl-3-O-(6-sulfo-alpha-D- quinovopyranosyl) glycerol (II), (2S)-1-O-palmitoyl-2-O-palmitoyl-3-O-(6'-sulfo-alpha-D- quinovopyranosyl) glycerol (III) and (2S)-1-O-palmitoyl-2-O-(11Z-octadecenoyl)-3-O-(6'-sulfo-alpha-D- quinovopyranosyl) glycerol (IV), stearic acid (V), methyl myristate(VI) and palmitic acid (VII).
Conclusion:
Compounds I-VI were isolated from the alga for the first time while I, II and IV are new natural products. I-IV showed activity causing morphological abnormality of P. oryzae mycelia.
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