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Updated: Sep 25, 2026

Mouse Lumbar Vertebra Uniaxial Compression Testing with Embedding of the Loading Surface
Published on: December 1, 2023
An inexpensive alternative approach to bone compression analyses
M C Rallo1, W O Shaffer, J W Standeven
1Theodore Cooper Surgical Research Institute, Departments of General and Orthopedic Surgery, Saint Louis University Health Sciences Center, 1402 South Grand Blvd., St. Louis, MO 63104, USA.
Abstract:
A new method for testing the compression strength of vertebrae was developed and implemented using minimal resources and time expenditure. The device digitally measured and analyzed the torque and force necessary to load rat lumbar and thoracic vertebrae to failure. The system was calibrated using a series of known lead masses. Similar to other standardized force/compression and torque devices, this method has been shown to provide reliable and reproducible results. Furthermore, although vertebrae were the only specimens used to collect data in these initial studies, this measurement system could be altered quite easily to allow for a variety of test materials.
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