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Updated: Jul 31, 2026
Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
Radiotherapy for in situ extramammary Paget disease of the vulva
G A Moreno-Arias1, C Conill, M A Sola-Casas
1Department of Dermatology, Hospital Clinic, University of Barcelona, Villaroel 170, 08036 Barcelona, Spain.
Background:
Radiotherapy as a first-choice treatment for in situ extramammary Paget disease has been successfully used.
Objectives:
To review the most relevant aspects of radiotherapy as first-choice treatment in selected cases of in situ extramammary Paget disease of the vulva.
Patients And Methods:
Two Caucasian females aged 76 and 92 years with in situ extramammary Paget disease localized in the genital region were treated by means of ortovoltage X-rays: 100 kV, 8 mA, 1.7 mm Al filter, field size of 12-cm cone, and source skin distance of 30 cm. Both patients received 40 Gy, 200 cGy per fraction, five fractions per week.
Results:
Complete regression of in situ extramammary Paget disease was observed in both patients after radical radiation therapy and neither local recurrences nor internal malignancies were detected.
Conclusions:
Radiotherapy is a curative treatment in selected cases of in situ extramammary Paget disease affecting the vulva.
