A quantitation of lactate dehydrogenase non-linearity

It was the objective of this study to quantitative the non-linearity seen in the lactate dehydrogenase reaction and relate these findings to the wide variation between reported values from various sources. Data are based upon two sample groupings: 1200 routine samples and 200 selected elevated specimens rangingg from 200 to 2000 I.U. (LD-L). This sample population demonstrated a rate of activity decrease rangin from 2% to 13% per minute, dependent upon activity level.