Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Low-grade malignant eccrine spiradenoma with systemic metastases.

Niamh Leonard1, David Smith, Paul McNamara

  • 1Department of Histopathology, Royal Victoria Infirmary, Newcastle-upon-Tyne, England, UK. niamh.leonard@rlbuh-tr.nwest.nhs.uk

The American Journal of Dermatopathology
|May 31, 2003
PubMed
Summary

Malignant eccrine spiradenoma (MES) is a rare cancer. This study presents a low-grade MES case with metastasis, highlighting vascular invasion as a potential prognostic indicator.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Th17 plasticity and transition toward a pathogenic cytokine signature are regulated by cyclosporine after allogeneic SCT.

Blood advances·2018
Same author

Alcohol Consumption in Diabetic Patients with Nonalcoholic Fatty Liver Disease.

Canadian journal of gastroenterology & hepatology·2017
Same author

Attacking the mosquito on multiple fronts: Insights from the Vector Control Optimization Model (VCOM) for malaria elimination.

PloS one·2017
Same author

Concurrent validity of the Partners in Health scale against general self-rated health in chronic conditions: A short report.

Chronic illness·2017
Same author

Ion chemistry at elevated ion-molecule interaction energies in a selected ion flow-drift tube: reactions of H<sub>3</sub>O<sup>+</sup>, NO<sup>+</sup> and O<sub>2</sub><sup>+</sup> with saturated aliphatic ketones.

Physical chemistry chemical physics : PCCP·2017
Same author

Co-occurring medical conditions in adults with Down syndrome: A systematic review toward the development of health care guidelines.

American journal of medical genetics. Part A·2017

Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Malignant eccrine spiradenoma (MES) is an exceptionally rare neoplasm.
  • MES can present as low-grade or high-grade tumors.
  • Systemic metastases are infrequently reported in MES cases.

Observation:

  • This report details an additional case of low-grade malignant eccrine spiradenoma with systemic metastases.
  • The observed low-grade MES exhibited a monotonous histological appearance, minimal pleomorphism, and few mitotic figures.
  • Vascular invasion was identified in this case and a previously reported low-grade MES case.

Findings:

  • Low-grade MES, while rare, can metastasize systemically.
  • Histological features of low-grade MES can be subtle, posing diagnostic challenges.

Related Experiment Videos

  • Vascular invasion appears to be a significant feature in low-grade MES with metastatic potential.

    • Implications:

    • The findings suggest that low-grade MES requires careful evaluation for metastatic potential.
    • Vascular invasion should be considered a critical prognostic factor in low-grade MES.
    • Further research is warranted to elucidate the behavior and management of low-grade MES.