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Evaluating the impact of stress on systemic disease: the MOST protocol in primary care

Jeffrey L Boone1, Jeffrey P Anthony

  • 1Health Sciences Center, University of Colorado, Denver, USA.

Insights

Mental stress significantly impacts physical health, leading to various conditions. Office-based testing can identify at-risk patients for stress-induced disorders, enabling timely management.

Area of Science:

  • Psychosomatic Medicine
  • Cardiology
  • Primary Care

Background:

  • Mental stress adversely affects physical health, manifesting in conditions like headaches, cardiovascular disease, and autoimmune disease flares.
  • The pervasive impact of stress necessitates effective identification and management strategies in primary care settings.

Purpose of the Study:

  • To highlight the importance of identifying and managing mental stress symptoms in primary care.
  • To introduce office-based mental stress testing as a tool for risk stratification.

Main Methods:

  • Utilizing office-based mental stress testing.
  • Employing cardiovascular markers to identify stress overresponders.
  • Assessing patients for risk of stress-induced disorders.

Main Results:

  • Office-based mental stress testing can identify individuals at higher risk for stress-induced disorders.
  • Early identification allows for targeted interventions to mitigate negative health outcomes.

Conclusions:

  • Primary care physicians can effectively manage mental stress using available testing and interventions.
  • Nonpharmacologic and pharmacologic interventions can improve stress response, reducing associated morbidity and mortality.

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