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Higher order ocular aberrations after cycloplegic and non-cycloplegic pupil dilation
Andrew Carkeet1, Shajan Velaedan, Yong Kang Tan
1Singapore Eye Research Institute, Singapore. lah_carkeet@yahoo.com.au
Summary
Cycloplegic eye exams show higher-order aberrations than non-cycloplegic ones. This difference impacts surgical correction strategies for visual imperfections.
Area of Science:
- Ophthalmology
- Optometry
- Vision Science
Background:
- Clinical aberrometry is frequently performed using mydriatic agents.
- Limited research exists on comparing aberrometry results with and without cycloplegia.
Purpose of the Study:
- To investigate differences in higher-order aberrations measured with and without cycloplegia.
- To assess the impact of cycloplegia on aberrometric measurements.
Main Methods:
- Higher-order aberrations were measured in 31 young subjects using a Bausch and Lomb Technolas Zywave Aberrometer.
- Measurements were taken under two conditions: with cyclopentolate hydrochloride (cycloplegia) and with phenylephrine hydrochloride (non-cycloplegia).
Main Results:
- Average higher-order aberrations (RMS) were significantly lower under phenylephrine (0.3852 µm) compared to cyclopentolate (0.4259 µm).
- Statistically significant differences were observed in vertical/horizontal coma and horizontal 5th-order aberrations between the two conditions.
- Repeatability RMS was similar (0.15 µm) for both conditions, while residual RMS was 0.22 µm.
Conclusions:
- Cycloplegic measurements yield different higher-order aberration values compared to non-cycloplegic measurements.
- These findings have implications for the surgical correction of higher-order aberrations.