Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Xenogeneic rejection among three botryllids (compound Ascidians).

Yasunori Saito1

  • 1Shimoda Marine Research Center, University of Tsukuba, Shizouka, Japan. saito@kurofune.shimoda.tsukuba.ac.jp

Zoological Science
|June 5, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical edge-case stress testing of two Asia-developed AI auto-contouring systems using prostate radiotherapy planning CT images.

Radiological physics and technology·2026
Same author

Dose reduction in radiotherapy treatment planning CT via deep learning-based reconstruction: a single‑institution study.

Radiological physics and technology·2025
Same author

Estimating organ dose with optimized peak dose index in cone-beam CT scans.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2024
Same author

Impact of Dose Perturbations Around Brachytherapy Seeds in External-Beam Radiotherapy Planning: A Fundamental and Clinical Validation Using Treatment Planning System-Based Monte Carlo Simulations.

Cureus·2023
Same author

Dosimetric and radiobiological analyses of a de-escalation strategy for elective nodal regions in human papillomavirus-associated oropharyngeal cancer.

Technical innovations & patient support in radiation oncology·2023
Same author

Validation of deep learning-based CT image reconstruction for treatment planning.

Scientific reports·2023
Same journal

Freshwater Colonization by a Scaleless Scale Worm: <i>Pisione mizuchi</i> sp. nov. (Annelida: Sigalionidae), from Sado Island, Japan.

Zoological science·2026
Same journal

Morphology and Phylogeny of <i>Notospermus psittacinus</i> comb. nov. (Nemertea: Pilidiophora: Lineidae) from Mindanao, Philippines.

Zoological science·2026
Same journal

<i>Levinaespira georgesnyderi</i> gen. et sp. nov., a New Deep-Sea Snail (Gastropoda: Neomphalidae) from Eastern Pacific Methane Seeps.

Zoological science·2026
Same journal

A New Species of Branchiobdellidan Symbiotic on Freshwater Crabs from Southern Japan, with a Supplemental Re-Description of <i>Cirrodrilus kawamurai</i>.

Zoological science·2026
Same journal

Effect of Relaxin-Like Gonad-Stimulating Peptide on Ovaries of the Sea Cucumber <i>Holothuria leucospilota</i>.

Zoological science·2026
Same journal

Differential Expression of Na<sup>+</sup>/K<sup>+</sup>-ATPase α -Subunit Isoforms in Functionally Distinct Types of Ionocytes in the Gills of Mozambique Tilapia.

Zoological science·2026
See all related articles

Xenogeneic rejection varies in botryllid tunicates. While Botryllus primigenus and Botrylloides simodensis show rejection upon contact, Botryllus scalaris does not, revealing distinct immune responses.

Area of Science:

  • Marine biology
  • Invertebrate immunology
  • Comparative immunology

Background:

  • Botryllid tunicates exhibit allogeneic recognition, but the mechanisms of xenogeneic rejection differ across species.
  • Understanding interspecies immune responses is crucial for marine invertebrate conservation and evolutionary studies.

Purpose of the Study:

  • To investigate and compare xenogeneic rejection reactions among three botryllid species: Botryllus scalaris, Botryllus primigenus, and Botrylloides simodensis.
  • To elucidate the relationship between allogeneic and xenogeneic rejection in these colonial tunicates.

Main Methods:

  • Colony contact experiments at natural growing edges and artificially cut surfaces.
  • Intravascular injection of xenogeneic blood plasma.
  • Observation and comparison of rejection responses across different experimental conditions and species.

Related Experiment Videos

Main Results:

  • Xenogeneic rejection occurred in Botryllus primigenus and Botrylloides simodensis during colony contact, mirroring their allogeneic rejection patterns.
  • Injection of xenogeneic blood plasma induced allogeneic-like rejection responses in all three species.
  • Botryllus scalaris notably failed to respond to injected xenogeneic blood plasma, unlike the other two species.

Conclusions:

  • Botryllid species display varied capacities for xenogeneic rejection, with distinct responses observed in contact versus injection assays.
  • The immune system's recognition of foreign tissues differs significantly among closely related botryllid species, highlighting evolutionary divergence in immune strategies.
  • Botryllus scalaris possesses a unique immunological profile regarding xenogeneic interactions compared to Botryllus primigenus and Botrylloides simodensis.